Pancreatic cancer
Adobe
The Market Online - At The Bell

Join our daily newsletter At The Bell to receive exclusive market insights

Amplia Therapeutics (ASX:ATX) has popped over +40% in lunchtime trades as the company reports its products provide superior outcomes when coupled with chemotherapy, at least in one ‘ACCENT’ trial announced on Thursday.

“The ACCENT trial is evaluating narmafotinib in combination with the chemotherapies gemcitabine and Abraxane in patients with advanced pancreatic cancer,” Amplia wrote on Thursday.

“Sufficient confirmed responses have now been recorded to demonstrate that narmafotinib combined with chemotherapy is superior to chemotherapy alone.”

Its drug, narmafotinib, is currently the subject of a pancreatic cancer trial which has, clearly, been on watchlists. Just look at liquidity.

Driving ATX’s +40% pop on Thursday is a dramatic shift in the number of shares trading hands each day. As of 1pm some 34.2M individual shares have moved on Amplia’s books, but over the last four weeks, the average daily amount has been only 166K.

That kind of effect is notorious for exaggerating share price gains. But Amplia’s good fortunes do also tap into a larger story for 2025 YTD – that a number of well-known biotech stocks have been, if not outperforming, then offering some good chances to make a few bags.

Currently, Amplia’s 1Y returns are up nearly +30%.

The most recent shock we saw to the healthcare sector was from, unsurprisingly, Donald Trump, who vowed to slash US drug prices.

So far, it’s not entirely clear how that will occur, and part of that uncertainty is perhaps in part why stocks like Telix and Neuren have been bouncing back from the sell-off that news caused.

ATX last traded at 8cps.

Join the discussion: See what HotCopper users are saying about ATX and be part of the conversations that move the markets.

ATX by the numbers
More From The Market Online
The Big Kahuna

Week 24 Wrap: WW3 looms (again); US econ data tepid & silver surfing

By and large, I don't think I'd be without peers when I said the biggest thing…
The Market Online Video

HotCopper Highlights, Week 24: Israel boosts Energy; Meeka eyes production & Mag7 back

Good Afternoon and welcome to HotCopper Highlights for Week 24 of the year, I’m Jon Davidson.…

HotCopper officially kicks off DealRoom, a groundbreaking Capital Raising service

Already Australia’s most popular and most-used finance website, HotCopper has officially kicked off DealRoom: a capital raising service
HotCopper Podcast Graphic which reads Episode 013 with copy that reads "They're changing the IPO rules and that's a good thing."

Listen: HotCopper Wire Podcast 013 – They changed the IPO rules (and that’s a good thing)

Welcome to this week’s HotCopper Wire, our market watch podcast!