DNA RNA therapy concept
Adobe Stock
The Market Online - At The Bell

Join our daily newsletter At The Bell to receive exclusive market insights

PYC Therapeutics (ASX:PYC) has been approved to escalate doses of its drug candidate VP-001, treating Retinitis Pigmentosa 11, in a second patient cohort. Dosages will be lifted to 75 micrograms (mcg).

The second cohort comprises patients part of the company’s Multiple Ascending Dose (MAD) study which runs alongside a Single Ascending Dose (SAD) study. Both Phase 1/2 studies are ongoing.

A safety review body ticked off on higher doses for the MAD group on Tuesday.

PYC reports that patients already doses with VP-001 in either stage of studies so far have shown “disease progression arrested and improved vision.”

Members of the SAD cohort have already taken 75mcg doses with no adverse effects, PYC reported on Tuesday. Higher doses in the MAD group will ultimately allow PYC to collect more data to present to regulators.

To that end, the company will approach the U.S. FDA in an attempt to win research fast-track status for its drug once data from the ongoing studies are back with the company (which is set for the first quarter of next year.)

Retinitis Pigmentosa type 11 is a genetic condition which can be simply described as a thickening of the retina.

Fluid abnormally collects in the eye after birth, the condition mainly affects children and generally causes blindness around middle age if left unchecked, according to the Lions Eye Institute.

PYC last traded at 19cps.

Join the discussion: See what HotCopper users are saying about PYC Therapeutics and be part of the conversations that move the markets.

The material provided in this article is for information only and should not be treated as investment advice. Viewers are encouraged to conduct their own research and consult with a certified financial advisor before making any investment decisions. For full disclaimer information, please click here.

PYC by the numbers
More From The Market Online
The Market Online Video

Timing will be everything for ‘smashing’ Hot Stock tip Judo Capital Holdings

Australian bank Judo Capital Holdings (ASX:JDO), best known for its finance and credit for small and medium-sized businesses, is
The Market Online Video

‘We’re looking’: Nickel-rich Indonesia sounds graphite warning to Aus producers

Nickel-rich Indonesia muscles in on Australian graphite producers as the Southeast Asian country expands into downstream…
Confused man

Aussie inflation seemingly hit a 3 year low. So why’s the ASX200 red?

Headline inflation in Australia has fallen to 2.8%, and that officially takes us into the RBA's…
Australia RBA politics concept

RBA holds rates as ALP election campaigning kicks off – expect more political focus

The Reserve Bank of Australia (RBA) has acted in line with wide-spread expectations and kept interest…